EMAS: Epigenome-Wide Mediation Analysis Study

DNA methylation is essential for human, and environment can change the DNA methylation and affect body status. Epigenome-Wide Mediation Analysis Study (EMAS) can find potential mediator CpG sites between exposure (x) and outcome (y) in epigenome-wide. For more information on the methods we used, please see the following references: Tingley, D. (2014) <doi:10.18637/jss.v059.i05>, Turner, S. D. (2018) <doi:10.21105/joss.00731>, Rosseel, D. (2012) <doi:10.18637/jss.v048.i02>.

Version: 0.2.2
Depends: R (≥ 4.1.0)
Imports: mediation, parallel, multilevel, minfi, ggplot2, qqman, lavaan, IlluminaHumanMethylationEPICanno.ilm10b4.hg19, IlluminaHumanMethylation450kanno.ilmn12.hg19
Published: 2022-08-11
Author: Xiuquan Nie [aut, cph, cre], Mengyi Wang [ctb, rev], Weihong Chen [fnd]
Maintainer: Xiuquan Nie <niexiuquan1995 at foxmail.com>
License: GPL-3
NeedsCompilation: no
CRAN checks: EMAS results

Documentation:

Reference manual: EMAS.pdf

Downloads:

Package source: EMAS_0.2.2.tar.gz
Windows binaries: r-devel: EMAS_0.2.2.zip, r-release: EMAS_0.2.1.zip, r-oldrel: EMAS_0.2.2.zip
macOS binaries: r-release (arm64): EMAS_0.2.2.tgz, r-oldrel (arm64): EMAS_0.2.2.tgz, r-release (x86_64): EMAS_0.2.1.tgz, r-oldrel (x86_64): EMAS_0.2.1.tgz
Old sources: EMAS archive

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