gprofiler2: Interface to the 'g:Profiler' Toolset

A toolset for functional enrichment analysis and visualization, gene/protein/SNP identifier conversion and mapping orthologous genes across species via 'g:Profiler' (<>). The main tools are: (1) 'g:GOSt' - functional enrichment analysis and visualization of gene lists; (2) 'g:Convert' - gene/protein/transcript identifier conversion across various namespaces; (3) 'g:Orth' - orthology search across species; (4) 'g:SNPense' - mapping SNP rs identifiers to chromosome positions, genes and variant effects. This package is an R interface corresponding to the 2019 update of 'g:Profiler' and provides access to 'g:Profiler' for versions 'e94_eg41_p11' and higher. See the package 'gProfileR' for accessing older versions from the 'g:Profiler' toolset.

Version: 0.2.3
Depends: R (≥ 3.5)
Imports: jsonlite, RCurl, ggplot2, plotly, tidyr (≥ 1.0.0), crosstalk, grDevices, gridExtra, grid, viridisLite, dplyr
Suggests: knitr, rmarkdown, prettydoc
Published: 2024-02-23
DOI: 10.32614/CRAN.package.gprofiler2
Author: Liis Kolberg, Uku Raudvere
Maintainer: Liis Kolberg <liis.kolberg at>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: no
Citation: gprofiler2 citation info
In views: Omics
CRAN checks: gprofiler2 results


Reference manual: gprofiler2.pdf
Vignettes: gprofiler2


Package source: gprofiler2_0.2.3.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): gprofiler2_0.2.3.tgz, r-oldrel (arm64): gprofiler2_0.2.3.tgz, r-release (x86_64): gprofiler2_0.2.3.tgz, r-oldrel (x86_64): gprofiler2_0.2.3.tgz
Old sources: gprofiler2 archive

Reverse dependencies:

Reverse imports: bulkAnalyseR, DFD, enrichViewNet, famat, GWENA, MultiRNAflow, orthogene, RCAS, scMappR, UniprotR
Reverse suggests: aPEAR, clustifyr, HPiP, knowYourCG, OmnipathR, rliger


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