Creates simulated clinical trial data with realistic correlation structures and assumed efficacy levels by using a tilted bootstrap resampling approach. Samples are drawn from observed data with some samples appearing more frequently than others. May also be used for simulating from a joint Bayesian distribution along with clinical trials based on the Bayesian distribution.
|Depends:||R (≥ 3.4.0)|
|Imports:||stats, quadprog, kernlab|
|Suggests:||knitr, rmarkdown, testthat, MASS, ggplot2|
|Author:||Nathan Morris [aut, cre], William Michael Landau [ctb], Eli Lilly and Company [cph]|
|Maintainer:||Nathan Morris <morris_nathan at lilly.com>|
|CRAN checks:||tboot results|
Tutorial on 'tboot'
Tutorial for 'BMR'
|Windows binaries:||r-devel: tboot_0.2.1.zip, r-release: tboot_0.2.1.zip, r-oldrel: tboot_0.2.1.zip|
|macOS binaries:||r-release (arm64): tboot_0.2.1.tgz, r-oldrel (arm64): tboot_0.2.1.tgz, r-release (x86_64): tboot_0.2.1.tgz, r-oldrel (x86_64): tboot_0.2.1.tgz|
|Old sources:||tboot archive|
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