visit: Phase I Dose Escalation Study Design for Vaccines

A Bayesian Phase I cancer vaccine trial design is implemented in this package. The design allows simultaneous evaluation of safety and immunogenicity outcomes in the context of vaccine studies. See Wang (2019) <doi:10.1002/sim.8021> for the details of the Phase I cancer vaccine trial design.

Version: 2.1
Depends: methods, R (≥ 3.5.0), rstan (≥ 2.19.2), Rcpp (≥ 1.0.2)
Imports: sqldf (≥ 0.4), parallel (≥ 3.2)
LinkingTo: BH (≥ 1.69.0-1), Rcpp (≥ 1.0.2), rstan (≥ 2.14), RcppEigen (≥ 0.3.3.5.0), StanHeaders (≥ 2.18.1-10)
Suggests: knitr, shiny, rmarkdown, pander, xtable
Published: 2019-08-26
Author: Zilu Wang [aut, cre] Chenguang Wang [aut, cre] Gary L Rosner [aut] Richard BS Roden [aut] Trustees of Columbia University [cph] (tools/make_cpp.R, R/stanmodels.R)
Maintainer: Chenguang Wang <cwang68 at jhmi.edu>
License: GPL (≥ 3)
NeedsCompilation: yes
SystemRequirements: GNU make
CRAN checks: visit results

Downloads:

Reference manual: visit.pdf
Vignettes: visit: Vaccine Phase I Design with Simultaneous Evaluation of Immnunogeneicity and Toxicity
Package source: visit_2.1.tar.gz
Windows binaries: r-devel: visit_2.1.zip, r-devel-gcc8: visit_2.1.zip, r-release: visit_2.1.zip, r-oldrel: visit_2.1.zip
OS X binaries: r-release: visit_2.1.tgz, r-oldrel: visit_2.1.tgz

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